Source Naturals Coenzymate B Complex Peppermint, 120 Tablets
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Source Naturals Coenzymate B Complex Peppermint, 120 Tablets Details
Manufacturer: Source NaturalsBrand: Source Naturals
Release Date: 2006-06-21
Model: SN0098
Product features:
- Goes directly into your bloodstream in its active form, ready to go to work immediately
- Natural peppermint flavor
- Also available in orange flavor
- Take 2 to 3 tablets daily, or as recommended by your health care professional
- Place tablet under the tongue and allow to dissolve slowly, altering the position of the tablet to avoid prolonged contact with the same area
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Customer Reviews of Source Naturals Coenzymate B Complex Peppermint, 120 Tablets
Customer Review: Recommended for people who are over age 51, with a possibility of pernicious anemia, and for people who do not eat meat.
Summary: 5 Stars
Sublingual Vitamin B12
Warning: I am not a doctor and do not play one on television. If you suspect you have a Vitamin B-12 deficiency (see below) you might need to receive Vitamin B-12 shots from your Medical doctor.
Vitamin B12 helps maintain healthy nerve cells and red blood cells [1-4]. It is also needed to help make DNA, the genetic material in all cells. Vitamin B12 is also called cobalamin because it contains the metal cobalt [1-4].
Vitamin B12 is bound to the protein in food. Hydrochloric acid in the stomach releases vitamin B12 from proteins in foods during digestion. Once released, vitamin B12 combines with a substance called intrinsic factor (IF). This complex can then be absorbed by the intestinal tract.
Vitamin B12 is naturally found in foods that come from animals, including fish, meat, poultry, eggs, milk, and milk products. Fortified breakfast cereals are a particularly valuable source of vitamin B12 for vegetarians [5-7]. Table 1 lists a variety of food sources of vitamin B12.
The DV for vitamin B12 is 6.0 micrograms ('g). Most food labels do not list a food's vitamin B12 content. The percent DV (%DV) listed on the table indicates the percentage of the DV provided in one serving. A food providing 5% of the DV or less is a low source while a food that provides 10% to 19% of the DV is a good source. A food that provides 20% or more of the DV is high in that nutrient. It is important to remember that foods that provide lower percentages of the DV also contribute to a healthful diet. For foods not listed in this table, please refer to the US Department of Agriculture's Nutrient Database Web site: http://www.nal.usda.gov/fnic/cgi-bin/nut_search.pl.
Recommendations for vitamin B12 are provided in the Dietary Reference Intakes (DRIs) developed by the Institute of Medicine of the National Academies [7]. Dietary Reference Intakes is the general term for a set of reference values used for planning and assessing nutrient intake for healthy people. Three important types of reference values included in the DRIs are Recommended Dietary Allowances (RDA), Adequate Intakes (AI), and Tolerable Upper Intake Levels (UL). The RDA recommends the average daily intake that is sufficient to meet the nutrient requirements of nearly all (97% to 98%) healthy individuals in each age and gender group [7]. An AI is set when there is insufficient scientific data available to establish an RDA. AIs meet or exceed the amount needed to maintain a nutritional state of adequacy in nearly all members of a specific age and gender group [7]. The UL, on the other hand, is the maximum daily intake unlikely to result in adverse health effects [7]. Table 2 lists the RDAs for vitamin B12, in micrograms, for children and adults.
Table 2: Recommended Dietary Allowances (RDA) for vitamin B12 for children and adults [7]
Age
(years) Males and Females
('g/day) Pregnancy
('g/day) Lactation
('g/day)
1-3 0.9 N/A N/A
4-8 1.2 N/A N/A
9-13 1.8 N/A N/A
14-18 2.4 2.6 2.8
19 and older 2.4 2.6 2.8
Information on vitamin B12 is insufficient to establish an RDA for infants. Therefore, an AI has been established that is based on the amount of vitamin B12 consumed by healthy infants who are fed breast milk [7]. Table 3 lists the AIs for vitamin B12, in micrograms, for infants.
Table 3: Adequate Intake (AI) for vitamin B12 for infants [7]
Age
(months) Males and Females
('g/day)
0-6 months 0.4
7-12 months 0.5
When is a deficiency of vitamin B12 likely to occur?
Results of two national surveys, the National Health and Nutrition Examination Survey (NHANES III-1988-94) [8] and the Continuing Survey of Food Intakes by Individuals (CSFII 1994-96) found that most children and adults in the United States (US) consume recommended amounts of vitamin B12 [6-8]. A deficiency may still occur as a result of an inability to absorb vitamin B12 from food and in strict vegetarians who do not consume any foods that come from animals [9]. As a general rule, most individuals who develop a vitamin B12 deficiency have an underlying stomach or intestinal disorder that limits the absorption of vitamin B12 [10]. Sometimes the only symptom of these intestinal disorders is subtly reduced cognitive function resulting from early vitamin B12 deficiency. Anemia and dementia follow later [1,11].
Signs, symptoms, and health problems associated with vitamin B12 deficiency:
* Characteristic signs, symptoms, and health problems associated with vitamin B12 deficiency include anemia, fatigue, weakness, constipation, loss of appetite, and weight loss [1,3,12].
* Deficiency also can lead to neurological changes such as numbness and tingling in the hands and feet [7,13].
* Additional symptoms of vitamin B12 deficiency are difficulty in maintaining balance, depression, confusion, dementia, poor memory, and soreness of the mouth or tongue [14].
* Signs of vitamin B12 deficiency in infancy include failure to thrive, movement disorders, delayed development, and megaloblastic anemia [15].
Many of these symptoms are very general and can result from a variety of medical conditions other than vitamin B12 deficiency. It is important to have a physician evaluate these symptoms so that appropriate medical care can be given.
Individuals with pernicious anemia
Anemia is a condition that occurs when there is insufficient hemoglobin in red blood cells to carry oxygen to cells and tissues. Common signs and symptoms of anemia include fatigue and weakness. Anemia can result from a variety of medical problems, including deficiencies of vitamin B12, vitamin B6, folate and iron. Pernicious anemia is the name given more than a century ago to describe the then-fatal vitamin B12 deficiency anemia that results from severe gastric atrophy, a condition that prevents gastric cells from secreting intrinsic factor. Intrinsic factor is a substance normally present in the stomach. Vitamin B12 must bind with intrinsic factor before it can be absorbed and used by your body [7,17-18]. An absence of intrinsic factor prevents normal absorption of vitamin B12 and results in pernicious anemia.
Most individuals with pernicious anemia need parenteral (deep subcutaneous) injections (shots) of vitamin B12 as initial therapy to replenish depleted body stores of vitamin B12. Vitamin B12 body stores can then be managed by a daily oral supplement of vitamin B12. A physician will manage the treatment required to maintain the vitamin B12 status of individuals with pernicious anemia.
Individuals with gastrointestinal disorders
Individuals with stomach and small intestine disorders may be unable to absorb enough vitamin B12 from food to maintain healthy body stores [19]. Intestinal disorders that may result in malabsorption of vitamin B12 include:
* Older adults
A good reason not to take acid blockers if not absolutely necessary.
Hydrochloric acid helps release vitamin B12 from the protein in food. This must occur before vitamin B12 binds with intrinsic factor and is absorbed in your intestines. Atrophic gastritis, which is an inflammation of the stomach, decreases the secretion of gastric juices, including hydrochloric acid. Less hydrochloric acid decreases the amount of vitamin B12 separated from proteins in foods and can result in poor absorption of vitamin B12 [10,22-26]. Decreased hydrochloric acid secretion also results in growth of normal bacteria in the small intestines. The bacteria may take up vitamin B12 for their own use, further contributing to a vitamin B12 deficiency [27].
Up to 30 percent of adults aged 50 years and older may have atrophic gastritis, an increased growth of intestinal bacteria, and be unable to normally absorb vitamin B12 in food. They are, however, able to absorb the synthetic vitamin B12 added to fortified foods and dietary supplements. Vitamin supplements and fortified foods may be the best sources of vitamin B12 for adults older than age 50 years [7].
Researchers have long been interested in the potential connection between vitamin B12 deficiency and dementia [28]. A recent review examined correlations between cognitive skills, homocysteine levels, and blood levels of folate, vitamin B12 and vitamin B6. The authors suggested that vitamin B12 deficiency may decrease levels of substances needed for the metabolism of neurotransmitters [29]. Neurotransmitters are chemicals that transmit nerve signals. Reduced levels of neurotransmitters may result in cognitive impairment. In 142 individuals considered at risk for dementia, researchers found that a daily supplement providing 2 milligrams (mg) folic acid and 1 mg vitamin B12, taken for 12 weeks, lowered homocysteine levels by 30%. They also demonstrated that cognitive impairment was significantly associated with elevated plasma total homocysteine. However, the decrease in homocysteine levels seen with the use of vitamin supplements did not improve cognition [30]. It is too soon to make any recommendations, but is an intriguing area of research.
Vegetarians
The popularity of vegetarian diets has risen along with an interest in avoiding meat and meat products for environmental, philosophical, and health reasons. However, the term vegetarianism is subject to a wide range of interpretations. Some people consider themselves to be vegetarian when they avoid red meat. Others believe that vegetarianism requires avoidance of all products that come from animals, including meat, poultry, fish, eggs, and dairy foods. The most commonly described forms of vegetarianism include:
* "lacto-ovo vegetarians", who avoid products that come from meat, poultry, and fish but consume eggs and dairy foods;
* "strict vegetarians", who avoid meat, poultry, fish, eggs, and dairy foods; and
* "vegans", who avoid meat, poultry, fish, eggs, and dairy foods and also do not use products that come from animals such as honey, leather, fur, silk, and wool.
Strict vegetarians and vegans are at greater risk of developing vitamin B12 deficiency than lacto-ovo vegetarians and nonvegetarians because natural food sources of vitamin B12 are limited to foods that come from animals [7]. Fortified cereals are one of the few sources of vitamin B12 from plants, and are an important dietary source of vitamin B12 for strict vegetarians and vegans. Strict vegetarians and vegans who do not consume foods that come from plants that are fortified with vitamin B12 need to consider taking a dietary supplement that contains vitamin B12 and should discuss the need for vitamin B12 supplements with their physician.
It is widely believed that vitamin B12 can be consistently obtained from nutritional yeasts. Consumers should be aware that these products may or may not contain added nutrients such as vitamin B12. Dietary supplements are regulated as foods rather than drugs, and companies that sell supplements such as nutritional yeasts fortified with vitamin B12 can legally change their formulation at any time. If you choose to supplement, select reliable sources of vitamin B12 and read product labels carefully.
When adults adopt a strict vegetarian diet, deficiency symptoms can be slow to appear. It may take years to deplete normal body stores of vitamin B12. However, breast-fed infants of women who follow strict vegetarian diets have very limited reserves of vitamin B12 and can develop a vitamin B12 deficiency within months [7]. This is of particular concern because undetected and untreated vitamin B12 deficiency in infants can result in permanent neurologic damage. Consequences of such neurologic damage are severe and can be irreversible. There are many case reports in the literature of infants and children who suffered consequences of vitamin B12 deficiency. It is very important for mothers who follow a strict vegetarian diet to consult with a pediatrician regarding appropriate use of vitamin B12 supplements for their infants and children [7].
Recommended for people who are over age 51, with a possibility of pernicious anemia, and for people who do not eat meat.
Gunner October, 2008
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Description of Source Naturals Coenzymate B Complex Peppermint, 120 Tablets
Dietary supplement. Suitable for vegetarians. In order for B Vitamins to be utilized by the body, they must first be converted into their active coenzyme forms. This sublingual Coenzymate B Complex goes directly into your bloodstream in its active form, ready to go to work immediately. (These statements have not been evaluated by the Food and Drug Administration. this product is not intended to diagnose, treat, cure or prevent any diseases.)Coenzyme Q10
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